USP2

gene product
UBP41
This gene encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease which is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase, murine double minute 2 (MDM2), MDM4/MDMX and cyclin D1. MDM2 and MDM4 are negative regulators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
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307 antibodies from 30 providers.

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AntibodyRefsTypeAVIWBELICCIPIHCFC
Proteintech Group
2 antibodies
Novus Biologicals
8 antibodies
Atlas Antibodies
2 antibodies
antibodies-online
85 antibodies
NovoPro Bioscience Inc.
2 antibodies
Abnova Corporation
12 antibodies
Biorbyt
11 antibodies
LifeSpan BioSciences, Inc.
65 antibodies
Aviva Systems Biology
6 antibodies
Abgent
5 antibodies
OriGene
9 antibodies
Acris Antibodies GmbH
9 antibodies
Invitrogen Antibodies
6 antibodies
ProSci
6 antibodies
St John's Laboratory
2 antibodies
Arigo
1 antibody
Boster Biological Technology
1 antibody
RabMAbs
1 antibody
NSJ Bioreagents
1 antibody
R&D Systems
1 antibody
United States Biological
48 antibodies
MyBioSource
8 antibodies
GeneTex
2 antibodies
Cell Signaling Technology, Inc
1 antibody
Sigma-Aldrich
2 antibodies
Creative Diagnostics
3 antibodies
Abbexa
3 antibodies
RayBiotech, Inc.
3 antibodies
Exalpha Biologicals, Inc.
1 antibody
GenWay
1 antibody