GHRL

gene product
ghrelin, MTLRP, obestatin
This gene encodes the ghrelin-obestatin preproprotein that is cleaved to yield two peptides, ghrelin and obestatin. Ghrelin is a powerful appetite stimulant and plays an important role in energy homeostasis. Its secretion is initiated when the stomach is empty, whereupon it binds to the growth hormone secretagogue receptor in the hypothalamus which results in the secretion of growth hormone (somatotropin). Ghrelin is thought to regulate multiple activities, including hunger, reward perception via the mesolimbic pathway, gastric acid secretion, gastrointestinal motility, and pancreatic glucose-stimulated insulin secretion. It was initially proposed that obestatin plays an opposing role to ghrelin by promoting satiety and thus decreasing food intake, but this action is still debated. Recent reports suggest multiple metabolic roles for obestatin, including regulating adipocyte function and glucose metabolism. Alternative splicing results in multiple transcript variants. In addition, antisense transcripts for this gene have been identified and may potentially regulate ghrelin-obestatin preproprotein expression. [provided by RefSeq, Nov 2014]
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787 antibodies from 36 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
antibodies-online
298 antibodies
Abnova Corporation
21 antibodies
Novus Biologicals
72 antibodies
Acris Antibodies GmbH
11 antibodies
OriGene
7 antibodies
Atlas Antibodies
1 antibody
NovoPro Bioscience Inc.
8 antibodies
GeneTex
17 antibodies
Abgent
8 antibodies
Affinity Biosciences
1 antibody
Antibodies.com
1 antibody
Everest Biotech
1 antibody
Proteintech Group
1 antibody
R&D Systems
3 antibodies
LifeSpan BioSciences, Inc.
68 antibodies
Invitrogen Antibodies
13 antibodies
Bioworld Technology, Inc
2 antibodies
Biorbyt
59 antibodies
St John's Laboratory
4 antibodies
NSJ Bioreagents
2 antibodies
Arigo
5 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
ProSci
12 antibodies
Aviva Systems Biology
3 antibodies
RayBiotech, Inc.
8 antibodies
Creative Diagnostics
11 antibodies
MyBioSource
4 antibodies
Abbiotec
1 antibody
Boster Biological Technology
1 antibody
Cell Signaling Technology, Inc
1 antibody
United States Biological
97 antibodies
Enzo Life Sciences
5 antibodies
GenWay
8 antibodies
Sigma-Aldrich
3 antibodies
EMD Millipore
5 antibodies