TLR5

gene product
FLJ10052, MGC126430, MGC126431, SLEB1, TIL3
This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease. [provided by RefSeq, Dec 2009]
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Antibodies

 

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Antibodypedia Validation Initiative

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Conjugate

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
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Validated within AVI
Eligible for validation within AVI
858 antibodies from 39 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
Enzo Life Sciences
3 antibodies
Abnova Corporation
19 antibodies
Novus Biologicals
59 antibodies
antibodies-online
267 antibodies
Invitrogen Antibodies
16 antibodies
Acris Antibodies GmbH
26 antibodies
OriGene
15 antibodies
GeneTex
6 antibodies
NSJ Bioreagents
3 antibodies
NovoPro Bioscience Inc.
1 antibody
LifeSpan BioSciences, Inc.
180 antibodies
Biorbyt
20 antibodies
Affinity Biosciences
4 antibodies
Rockland Immunochemicals, Inc.
3 antibodies
ABEOMICS Inc.
7 antibodies
Aviva Systems Biology
9 antibodies
R&D Systems
8 antibodies
Bioworld Technology, Inc
1 antibody
Proteintech Group
1 antibody
Abgent
8 antibodies
ProSci
3 antibodies
Boster Biological Technology
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
MyBioSource
14 antibodies
Abbiotec
3 antibodies
Santa Cruz Biotechnology
1 antibody
BioLegend
3 antibodies
FabGennix
3 antibodies
GenWay
6 antibodies
Abiocode, Inc.
2 antibodies
United States Biological
120 antibodies
RayBiotech, Inc.
5 antibodies
Creative Diagnostics
5 antibodies
Sigma-Aldrich
2 antibodies
St John's Laboratory
1 antibody
Abbexa
3 antibodies
Exalpha Biologicals, Inc.
2 antibodies
RabMAbs
1 antibody