Tissue expression
Cell line expression
Protein structure
PHGDH
Phosphoglycerate dehydrogenasePDG, PGDH, SERA
This gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms. Multiple alternatively spliced transcript variants have been found, however the full-length nature of most are not known. [provided by RefSeq, Aug 2011]
Top validated antibodies |
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Proteintech Group | 14719-1-AP | 49 references | Polyclonal |
WB
EL
ICC
IP
IHC
|
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Novus Biologicals | H00026227-M01 | 1 references | Monoclonal |
WB
EL
ICC
IP
IHC
|
|
Invitrogen Antibodies | PA5-27578 | 1 references | Polyclonal |
WB
ICC
IP
IHC
OA
|
|
Atlas Antibodies | HPA021241 | 6 references | Polyclonal |
WB
ICC
IHC
|
|
antibodies-online | ABIN565240 | 1 references | Monoclonal |
WB
EL
ICC
IP
IHC
|
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Supportive data in Antibodypedia
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Recommended by provider