CAV1

gene product
CAV
The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1. [provided by RefSeq, Mar 2010]
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AntibodyRefsTypeWBELICCIPIHCFC
Invitrogen Antibodies
13 antibodies
Novus Biologicals
49 antibodies
antibodies-online
394 antibodies
GeneTex
10 antibodies
Cell Signaling Technology, Inc
4 antibodies
Biorbyt
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Proteintech Group
2 antibodies
LifeSpan BioSciences, Inc.
187 antibodies
NovoPro Bioscience Inc.
13 antibodies
Affinity Biosciences
4 antibodies
NSJ Bioreagents
3 antibodies
Abnova Corporation
16 antibodies
Atlas Antibodies
1 antibody
Boster Biological Technology
3 antibodies
Acris Antibodies GmbH
35 antibodies
St John's Laboratory
13 antibodies
Aviva Systems Biology
10 antibodies