Tissue expression
Cell line expression
Protein structure

PTK2B

Protein tyrosine kinase 2 beta
CADTK, CAKB, FAK2, PTK, PYK2, RAFTK 
This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
More gene data

All Antibodies

 

Filters

Application

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antigen sequence

Epitope

Antibody

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
1234 antibodies from 45 providers.

Antibody properties

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
Invitrogen Antibodies
49 antibodies
GeneTex
16 antibodies
antibodies-online
367 antibodies
OriGene
19 antibodies
Novus Biologicals
13 antibodies
Proteintech Group
3 antibodies
Abnova Corporation
16 antibodies
Biorbyt
198 antibodies
NovoPro Bioscience Inc.
13 antibodies
Acris Antibodies GmbH
17 antibodies
Cusabio Biotech Co., Ltd
18 antibodies
Aviva Systems Biology
13 antibodies
Arigo
3 antibodies
Signalway Antibody LLC
2 antibodies
Cell Signaling Technology, Inc
4 antibodies
St John's Laboratory
18 antibodies
Boster Biological Technology
7 antibodies
Affinity Biosciences
5 antibodies
ProSci
8 antibodies
FineTest Biotech
2 antibodies
Abgent
11 antibodies
HUABIO Research
1 antibody
Atlas Antibodies
2 antibodies
FabGennix
3 antibodies
R&D Systems
3 antibodies
Aladdin Scientific
1 antibody
Bioworld Technology, Inc
5 antibodies
Bethyl Laboratories
2 antibodies
RabMAbs
6 antibodies
Abbkine Scientific Co.Ltd.
8 antibodies
Creative Biolabs
34 antibodies
MilliporeSigma / Merck KGaA
16 antibodies
MyBioSource
9 antibodies
BioLegend
1 antibody
SignalChem
1 antibody
United States Biological
99 antibodies
Abbexa
24 antibodies
Leading Biology
11 antibodies
Creative Diagnostics
5 antibodies
RayBiotech, Inc.
5 antibodies
EMD Millipore
5 antibodies
GenWay
4 antibodies
Abbiotec
1 antibody