Tissue expression
Cell line expression
Protein structure
AIMP1
Aminoacyl tRNA synthetase complex interacting multifunctional protein 1EMAP-2, EMAPII, p43, SCYE1
The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20. [provided by RefSeq, Dec 2008]
Top validated antibodies |
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Proteintech Group | 11091-1-AP | 6 references | Polyclonal |
WB
EL
ICC
IP
IHC
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Atlas Antibodies | HPA018476 | Polyclonal |
WB
ICC
IHC
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Invitrogen Antibodies | PA5-117774 | Polyclonal |
WB
EL
ICC
IP
IHC
OA |
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Affinity Biosciences | DF7261 | Polyclonal |
WB
EL
ICC
IP
IHC
FC |
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GeneTex | GTX105175 | 1 references | Polyclonal |
WB
ICC
IHC
|
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