Tissue expression
Cell line expression

MKRN1

gene product
RNF61 
This gene encodes a protein that belongs to a novel class of zinc finger proteins. The encoded protein functions as a transcriptional co-regulator, and as an E3 ubiquitin ligase that promotes the ubiquitination and proteasomal degradation of target proteins. The protein encoded by this gene is thought to regulate RNA polymerase II-catalyzed transcription. Substrates for this protein's E3 ubiquitin ligase activity include the capsid protein of the West Nile virus and the catalytic subunit of the telomerase ribonucleoprotein. This protein controls cell cycle arrest and apoptosis by regulating p21, a cell cycle regulator, and the tumor suppressor protein p53. Pseudogenes of this gene are present on chromosomes 1, 3, 9, 12 and 20, and on the X chromosome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014]
More gene data

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361 antibodies from 29 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
Invitrogen Antibodies
15 antibodies
Novus Biologicals
54 antibodies
antibodies-online
98 antibodies
LifeSpan BioSciences, Inc.
49 antibodies
OriGene
13 antibodies
GeneTex
2 antibodies
Abnova Corporation
5 antibodies
Antibodies.com
2 antibodies
Cusabio Biotech Co., Ltd
4 antibodies
Bethyl Laboratories
2 antibodies
Acris Antibodies GmbH
3 antibodies
Everest Biotech
2 antibodies
NSJ Bioreagents
2 antibodies
Biorbyt
14 antibodies
Aviva Systems Biology
4 antibodies
Abgent
3 antibodies
ProSci
5 antibodies
Abiocode, Inc.
2 antibodies
Proteintech Group
1 antibody
MyBioSource
6 antibodies
Creative Diagnostics
4 antibodies
Creative Biolabs
5 antibodies
MilliporeSigma / Merck KGaA
5 antibodies
RayBiotech, Inc.
1 antibody
United States Biological
38 antibodies
Leading Biology
3 antibodies
Abbexa
6 antibodies
GenWay
1 antibody