CTSB

gene product
This gene encodes a member of the C1 family of peptidases. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the cathepsin B light and heavy chains, which can dimerize to form the double chain form of the enzyme. This enzyme is a lysosomal cysteine protease with both endopeptidase and exopeptidase activity that may play a role in protein turnover. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer's disease, the most common cause of dementia. Overexpression of the encoded protein has been associated with esophageal adenocarcinoma and other tumors. Multiple pseudogenes of this gene have been identified. [provided by RefSeq, Nov 2015]
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619 antibodies from 38 providers.

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Novus Biologicals
48 antibodies
R&D Systems
7 antibodies
Atlas Antibodies
1 antibody
NovoPro Bioscience Inc.
4 antibodies
GeneTex
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antibodies-online
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Aviva Systems Biology
6 antibodies
OriGene
6 antibodies
Cell Signaling Technology, Inc
5 antibodies
Boster Biological Technology
3 antibodies
Abgent
3 antibodies
Enzo Life Sciences
2 antibodies
Biorbyt
37 antibodies
LifeSpan BioSciences, Inc.
108 antibodies
Invitrogen Antibodies
6 antibodies
Proteintech Group
1 antibody
Affinity Biosciences
2 antibodies
Acris Antibodies GmbH
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Bioworld Technology, Inc
2 antibodies
ProSci
1 antibody
RabMAbs
3 antibodies
St John's Laboratory
3 antibodies
Creative Biolabs
41 antibodies
Creative Diagnostics
9 antibodies
Abbkine Scientific Co.Ltd.
2 antibodies
Abnova Corporation
5 antibodies
NSJ Bioreagents
2 antibodies
MyBioSource
13 antibodies
BioLegend
1 antibody
Sino Biological Inc.
1 antibody
RayBiotech, Inc.
2 antibodies
United States Biological
64 antibodies
Abbexa
3 antibodies
Sigma-Aldrich
2 antibodies
EMD Millipore
1 antibody
Molecular Innovations
1 antibody
GenWay
6 antibodies