CTSB

gene product
The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
More gene data

Featured antibodies

Antibodies

 

Filters

Antibodypedia Validation Initiative

Validation method

Application

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Validated within AVI
Eligible for validation within AVI
451 antibodies from 38 providers.

Antibody properties

Applications

or Cancel
AntibodyRefsTypeAVIWBELICCIPIHCFC
R&D Systems
7 antibodies
Atlas Antibodies
1 antibody
NovoPro Bioscience Inc.
4 antibodies
GeneTex
7 antibodies
antibodies-online
122 antibodies
Aviva Systems Biology
6 antibodies
Novus Biologicals
27 antibodies
OriGene
6 antibodies
Cell Signaling Technology, Inc
4 antibodies
Abgent
3 antibodies
Enzo Life Sciences
2 antibodies
LifeSpan BioSciences, Inc.
77 antibodies
Invitrogen Antibodies
6 antibodies
Proteintech Group
1 antibody
Biorbyt
30 antibodies
Affinity Biosciences
2 antibodies
Acris Antibodies GmbH
7 antibodies
Bioworld Technology, Inc
2 antibodies
ProSci
1 antibody
Boster Biological Technology
3 antibodies
RabMAbs
3 antibodies
St John's Laboratory
3 antibodies
Creative Diagnostics
8 antibodies
Abbkine Scientific Co.Ltd.
2 antibodies
Abnova Corporation
5 antibodies
Creative Biolabs
5 antibodies
MyBioSource
13 antibodies
BioLegend
1 antibody
NSJ Bioreagents
1 antibody
Sino Biological Inc.
1 antibody
RayBiotech, Inc.
2 antibodies
United States Biological
64 antibodies
Abbexa
3 antibodies
Sigma-Aldrich
2 antibodies
EMD Millipore
1 antibody
Molecular Innovations
1 antibody
GenWay
6 antibodies