ZNF81

This gene encodes a protein that likely functions as a transcription factor. The protein contains an N-terminal KRAB domain and several C2H2-type zinc finger motifs. Mutations in this gene cause an X-linked form of intellectual disability (MRX45). Microduplication of a region of chromosome X including this gene has also been associated with other forms of intellectual disability. [provided by RefSeq, Jul 2017]

Description

zinc finger protein 81

Protein family

Disease related genes, Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Predicted intracellular proteins, Protein evidence (Peptideatlas), Transcription factors

Chromosome

X:p11.23 (47836902 - 48002561)

Ensembl ID

ENSG00000197779  (ver. 99.38)

Orthologs

-

UniProt

P51508

neXtProt

NX_P51508

Human splice variants