Tissue expression
Cell line expression
Protein structure

INS

Insulin
IDDM1, IDDM2 
This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified, including insulin-dependent diabetes mellitus, permanent neonatal diabetes diabetes mellitus, maturity-onset diabetes of the young type 10 and hyperproinsulinemia. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. [provided by RefSeq, May 2020]
More gene data

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3780 antibodies from 52 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
Proteintech Group
5 antibodies
Novus Biologicals
507 antibodies
Invitrogen Antibodies
117 antibodies
GeneTex
55 antibodies
Atlas Antibodies
1 antibody
OriGene
55 antibodies
NSJ Bioreagents
18 antibodies
Abgent
17 antibodies
NovoPro Bioscience Inc.
17 antibodies
Biorbyt
357 antibodies
antibodies-online
1259 antibodies
Boster Biological Technology
6 antibodies
R&D Systems
21 antibodies
Antibodies.com
4 antibodies
Acris Antibodies GmbH
50 antibodies
Affinity Biosciences
2 antibodies
FineTest Biotech
2 antibodies
Cusabio Biotech Co., Ltd
8 antibodies
Cell Signaling Technology, Inc
8 antibodies
St John's Laboratory
7 antibodies
HUABIO Research
4 antibodies
Exalpha Biologicals, Inc.
1 antibody
Enzo Life Sciences
3 antibodies
Bioworld Technology, Inc
4 antibodies
Abbkine Scientific Co.Ltd.
2 antibodies
United States Biological
119 antibodies
Abnova Corporation
37 antibodies
MyBioSource
37 antibodies
Leading Biology
31 antibodies
Aviva Systems Biology
34 antibodies
ProSci
8 antibodies
SICGEN
2 antibodies
Creative Biolabs
193 antibodies
Creative Diagnostics
26 antibodies
Abbexa
25 antibodies
RabMAbs
4 antibodies
ABEOMICS Inc.
1 antibody
Rockland Immunochemicals, Inc.
1 antibody
RayBiotech, Inc.
14 antibodies
Absolute Antibody
9 antibodies
Abbiotec
3 antibodies
QED Bioscience
2 antibodies
MilliporeSigma / Merck KGaA
2 antibodies
Aladdin Scientific
1 antibody
Molecular Depot LLC
1 antibody
EMD Millipore
4 antibodies
Mabtech
4 antibodies
Nordic BioSite
2 antibodies
Aalto Bio Reagents Ltd.
1 antibody