Tissue expression
Cell line expression
Protein structure
DGCR8
DGCR8 microprocessor complex subunitC22orf12, DGCRK6, Gy1, pasha
This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
Top validated antibodies |
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Proteintech Group | ![]() |
85 references | Polyclonal |
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Invitrogen Antibodies | ![]() |
Polyclonal |
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NovoPro Bioscience Inc. | ![]() |
Polyclonal |
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FineTest Biotech | ![]() |
Polyclonal |
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Biorbyt | ![]() |
Polyclonal |
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