Tissue expression
Cell line expression
Protein structure
MITF
Melanocyte inducing transcription factorbHLHe32, MI, WS2, WS2A
The protein encoded by this gene is a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. The encoded protein regulates melanocyte development and is responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. [provided by RefSeq, Aug 2017]
Top validated antibodies |
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| NSJ Bioreagents | Monoclonal |
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| Proteintech Group | 30 references | Polyclonal |
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| Invitrogen Antibodies | 2 references | Monoclonal |
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| Atlas Antibodies | 26 references | Polyclonal |
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| OriGene | 1 references | Monoclonal |
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