Tissue expression
Cell line expression
Protein structure
TNFAIP3
TNF alpha induced protein 3A20, OTUD7C
This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2012]
Top validated antibodies |
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Novus Biologicals | ![]() |
40 references | Monoclonal |
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LSBio | ![]() |
Polyclonal |
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GeneTex | ![]() |
Monoclonal |
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Invitrogen Antibodies | ![]() |
Monoclonal |
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OriGene | ![]() |
1 references | Polyclonal |
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