CDK6

gene product
PLSTIRE
The protein encoded by this gene is a member of the CMGC family of serine/threonine protein kinases. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Altered expression of this gene has been observed in multiple human cancers. A mutation in this gene resulting in reduced cell proliferation, and impaired cell motility and polarity, and has been identified in patients with primary microcephaly. [provided by RefSeq, Aug 2017]
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924 antibodies from 38 providers.

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Novus Biologicals
8 antibodies
Invitrogen Antibodies
8 antibodies
Abnova Corporation
13 antibodies
Atlas Antibodies
1 antibody
GeneTex
15 antibodies
antibodies-online
340 antibodies
LifeSpan BioSciences, Inc.
175 antibodies
NovoPro Bioscience Inc.
3 antibodies
Proteintech Group
3 antibodies
Santa Cruz Biotechnology
1 antibody
Acris Antibodies GmbH
21 antibodies
OriGene
21 antibodies
Biorbyt
51 antibodies
Arigo
4 antibodies
Signalway Antibody LLC
4 antibodies
Boster Biological Technology
8 antibodies
NSJ Bioreagents
4 antibodies
Bioworld Technology, Inc
2 antibodies
St John's Laboratory
7 antibodies
Affinity Biosciences
5 antibodies
ProSci
8 antibodies
Abgent
4 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Aviva Systems Biology
10 antibodies
Cell Signaling Technology, Inc
2 antibodies
RabMAbs
3 antibodies
Bethyl Laboratories
1 antibody
Creative Diagnostics
9 antibodies
Creative Biolabs
29 antibodies
Abbiotec
2 antibodies
RayBiotech, Inc.
2 antibodies
United States Biological
98 antibodies
MyBioSource
14 antibodies
GenWay
3 antibodies
Sigma-Aldrich
4 antibodies
Exalpha Biologicals, Inc.
1 antibody
EMD Millipore
2 antibodies