Tissue expression
Cell line expression
Protein structure
SLC9A3R1
SLC9A3 regulator 1EBP50, NHERF, NHERF1
This gene encodes a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer. [provided by RefSeq, Sep 2009]
Top validated antibodies |
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Invitrogen Antibodies | ![]() |
41 references | Polyclonal |
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Novus Biologicals | ![]() |
3 references | Polyclonal |
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Atlas Antibodies | ![]() |
Polyclonal |
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antibodies-online | ![]() |
3 references | Polyclonal |
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Abnova Corporation | ![]() |
Monoclonal |
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