MAX

gene product
bHLHd4, bHLHd5, bHLHd6, bHLHd7, bHLHd8
The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
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Antibodies

 

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Antibodypedia Validation Initiative

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  or   Clear
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Eligible for validation within AVI
505 antibodies from 36 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
7 antibodies
Santa Cruz Biotechnology
1 antibody
Abnova Corporation
7 antibodies
NovoPro Bioscience Inc.
5 antibodies
Biorbyt
28 antibodies
Arigo
3 antibodies
antibodies-online
179 antibodies
Invitrogen Antibodies
6 antibodies
Bioworld Technology, Inc
3 antibodies
Affinity Biosciences
4 antibodies
LifeSpan BioSciences, Inc.
89 antibodies
St John's Laboratory
6 antibodies
NSJ Bioreagents
3 antibodies
Cell Signaling Technology, Inc
2 antibodies
Bethyl Laboratories
1 antibody
Boster Biological Technology
1 antibody
GeneTex
9 antibodies
Atlas Antibodies
1 antibody
R&D Systems
1 antibody
Proteintech Group
1 antibody
Antibodies.com
1 antibody
Aviva Systems Biology
6 antibodies
Everest Biotech
1 antibody
OriGene
6 antibodies
Acris Antibodies GmbH
6 antibodies
Creative Biolabs
2 antibodies
ProSci
3 antibodies
Sino Biological Inc.
3 antibodies
MyBioSource
8 antibodies
United States Biological
74 antibodies
Abbkine Scientific Co.Ltd.
2 antibodies
Sigma-Aldrich
5 antibodies
Abbexa
3 antibodies
GenWay
3 antibodies
Abgent
1 antibody