Tissue expression
Cell line expression
Protein structure
CFL1
Cofilin 1CFL
The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus. [supplied by OMIM, Apr 2004]
Top validated antibodies |
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| GeneTex | 12 references | Polyclonal |
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| Proteintech Group | 27 references | Polyclonal |
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| Novus Biologicals | 4 references | Monoclonal |
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| antibodies-online | 5 references | Monoclonal |
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| Abnova Corporation | 3 references | Monoclonal |
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