ADGRE5

gene product
CD97, TM7LN1
This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19. [provided by RefSeq, Jun 2011]
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Antibodies

 

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Antibodypedia Validation Initiative

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761 antibodies from 39 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
GeneTex
15 antibodies
Boster Biological Technology
1 antibody
antibodies-online
241 antibodies
Novus Biologicals
71 antibodies
Invitrogen Antibodies
11 antibodies
NovoPro Bioscience Inc.
5 antibodies
Atlas Antibodies
1 antibody
R&D Systems
26 antibodies
Proteintech Group
1 antibody
Biorbyt
43 antibodies
Acris Antibodies GmbH
12 antibodies
Affinity Biosciences
2 antibodies
Abnova Corporation
12 antibodies
OriGene
13 antibodies
Aviva Systems Biology
13 antibodies
Abgent
5 antibodies
LifeSpan BioSciences, Inc.
131 antibodies
Antibodies.com
3 antibodies
RabMAbs
4 antibodies
St John's Laboratory
4 antibodies
Rockland Immunochemicals, Inc.
1 antibody
BioLegend
7 antibodies
Everest Biotech
1 antibody
NSJ Bioreagents
1 antibody
ProSci
2 antibodies
Sino Biological Inc.
10 antibodies
Miltenyi Biotec
16 antibodies
United States Biological
49 antibodies
Creative Diagnostics
14 antibodies
MyBioSource
8 antibodies
EMD Millipore
1 antibody
GenWay
10 antibodies
RayBiotech, Inc.
5 antibodies
Abbexa
2 antibodies
Abbkine Scientific Co.Ltd.
2 antibodies
Arigo
2 antibodies
Sigma-Aldrich
2 antibodies
eBioscience, An Affymetrix Company
2 antibodies