TUBA1A

gene product
B-ALPHA-1, FLJ25113, TUBA3
Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q. Mutations in this gene cause lissencephaly type 3 (LIS3) - a neurological condition characterized by microcephaly, mental retardation, and early-onset epilepsy and caused by defective neuronal migration. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012]
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554 antibodies from 31 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
antibodies-online
236 antibodies
Novus Biologicals
89 antibodies
Invitrogen Antibodies
18 antibodies
Proteintech Group
2 antibodies
GeneTex
3 antibodies
Abnova Corporation
1 antibody
Aviva Systems Biology
6 antibodies
Biorbyt
34 antibodies
OriGene
15 antibodies
Affinity Biosciences
3 antibodies
NovoPro Bioscience Inc.
6 antibodies
Atlas Antibodies
2 antibodies
St John's Laboratory
17 antibodies
Abbkine Scientific Co.Ltd.
29 antibodies
R&D Systems
1 antibody
LifeSpan BioSciences, Inc.
26 antibodies
Signalway Antibody LLC
2 antibodies
Acris Antibodies GmbH
7 antibodies
Abgent
3 antibodies
Boster Biological Technology
1 antibody
Creative Diagnostics
9 antibodies
ProSci
4 antibodies
Sigma-Aldrich
2 antibodies
EMD Millipore
10 antibodies
MyBioSource
16 antibodies
GenWay
2 antibodies
Bioworld Technology, Inc
1 antibody
Abiocode, Inc.
1 antibody
RabMAbs
1 antibody
United States Biological
4 antibodies
Abbexa
3 antibodies