Tissue expression
Cell line expression

CREBBP

gene product
CBP, KAT3A, RSTS, RTS 
This gene is ubiquitously expressed and is involved in the transcriptional coactivation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition. The protein encoded by this gene has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex. This protein acetylates both histone and non-histone proteins. This protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain. Mutations in this gene cause Rubinstein-Taybi syndrome (RTS). Chromosomal translocations involving this gene have been associated with acute myeloid leukemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2009]
More gene data

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764 antibodies from 40 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Invitrogen Antibodies
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antibodies-online
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Novus Biologicals
27 antibodies
Atlas Antibodies
1 antibody
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Cell Signaling Technology, Inc
3 antibodies
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5 antibodies
Acris Antibodies GmbH
11 antibodies
Aviva Systems Biology
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LifeSpan BioSciences, Inc.
164 antibodies
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Affinity Biosciences
2 antibodies
NovoPro Bioscience Inc.
4 antibodies
R&D Systems
1 antibody
Santa Cruz Biotechnology
1 antibody
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3 antibodies
Bioworld Technology, Inc
2 antibodies
Bethyl Laboratories
3 antibodies
Abgent
4 antibodies
SignalChem
1 antibody
Abbkine Scientific Co.Ltd.
3 antibodies
Creative Biolabs
21 antibodies
Arigo
4 antibodies
Abbexa
35 antibodies
MyBioSource
12 antibodies
RabMAbs
2 antibodies
Creative Diagnostics
6 antibodies
RayBiotech, Inc.
4 antibodies
United States Biological
76 antibodies
Spring Bioscience
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Leading Biology
4 antibodies
GenWay
5 antibodies
ProSci
3 antibodies
Abiocode, Inc.
1 antibody
Absolute Antibody
5 antibodies
MilliporeSigma / Merck KGaA
3 antibodies
Rockland Immunochemicals, Inc.
2 antibodies