PLCG1

gene product
NCKAP3, PLC-II, PLC1, PLC148, PLCgamma1
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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1074 antibodies from 36 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Abnova Corporation
13 antibodies
Novus Biologicals
63 antibodies
antibodies-online
413 antibodies
Santa Cruz Biotechnology
1 antibody
Cell Signaling Technology, Inc
11 antibodies
Invitrogen Antibodies
10 antibodies
Signalway Antibody LLC
5 antibodies
Atlas Antibodies
2 antibodies
LifeSpan BioSciences, Inc.
121 antibodies
Affinity Biosciences
9 antibodies
Aviva Systems Biology
13 antibodies
NovoPro Bioscience Inc.
8 antibodies
Biorbyt
54 antibodies
Boster Biological Technology
2 antibodies
Abgent
12 antibodies
OriGene
22 antibodies
Acris Antibodies GmbH
18 antibodies
GeneTex
13 antibodies
Arigo
2 antibodies
Bioworld Technology, Inc
6 antibodies