ITGB4

gene product
CD104
Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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Antibodies

 

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Antibodypedia Validation Initiative

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  or   Clear
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Eligible for validation within AVI
940 antibodies from 39 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
Abgent
3 antibodies
GeneTex
17 antibodies
Novus Biologicals
93 antibodies
antibodies-online
355 antibodies
Biorbyt
45 antibodies
Acris Antibodies GmbH
26 antibodies
OriGene
17 antibodies
Santa Cruz Biotechnology
1 antibody
Invitrogen Antibodies
13 antibodies
NovoPro Bioscience Inc.
3 antibodies
R&D Systems
22 antibodies
Proteintech Group
1 antibody
Atlas Antibodies
2 antibodies
LifeSpan BioSciences, Inc.
149 antibodies
NSJ Bioreagents
4 antibodies
Boster Biological Technology
4 antibodies
Aviva Systems Biology
15 antibodies
Cell Signaling Technology, Inc
2 antibodies
Affinity Biosciences
1 antibody
Abnova Corporation
11 antibodies