GCLC

gene product
GCS, GLCL, GLCLC
Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction. [provided by RefSeq, Oct 2010]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI
421 antibodies from 33 providers.

Antibody properties

General

Applications

or Cancel
Antibody
Proteintech Group
1 antibody
antibodies-online
124 antibodies
Novus Biologicals
28 antibodies
Abnova Corporation
3 antibodies
Biorbyt
19 antibodies
OriGene
10 antibodies
Acris Antibodies GmbH
6 antibodies
NSJ Bioreagents
4 antibodies
Invitrogen Antibodies
12 antibodies
Santa Cruz Biotechnology
1 antibody
Aviva Systems Biology
4 antibodies
GeneTex
3 antibodies
NovoPro Bioscience Inc.
5 antibodies
Atlas Antibodies
2 antibodies
LifeSpan BioSciences, Inc.
103 antibodies
Abgent
4 antibodies
HUABIO Research
1 antibody
Boster Biological Technology
3 antibodies
Affinity Biosciences
1 antibody
ProSci
3 antibodies
MyBioSource
6 antibodies
Bioss
1 antibody
United States Biological
47 antibodies
RayBiotech, Inc.
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Creative Biolabs
10 antibodies
St John's Laboratory
2 antibodies
Leading Biology
4 antibodies
Sigma-Aldrich
3 antibodies
Creative Diagnostics
2 antibodies
Bioworld Technology, Inc
1 antibody
Abbexa
4 antibodies
GenWay
1 antibody