PGK1

gene product
The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. Additionally, this protein is secreted by tumor cells where it participates in angiogenesis by functioning to reduce disulfide bonds in the serine protease, plasmin, which consequently leads to the release of the tumor blood vessel inhibitor angiostatin. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Deficiency of the enzyme is associated with a wide range of clinical phenotypes hemolytic anemia and neurological impairment. Pseudogenes of this gene have been defined on chromosomes 19, 21 and the X chromosome. [provided by RefSeq, Jan 2014]
More gene data

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI
474 antibodies from 37 providers.

Antibody properties

General

Applications

or Cancel
Antibody
GeneTex
4 antibodies
Abgent
3 antibodies
Novus Biologicals
8 antibodies
Invitrogen Antibodies
11 antibodies
Biorbyt
31 antibodies
Proteintech Group
1 antibody
antibodies-online
167 antibodies
NSJ Bioreagents
6 antibodies
Arigo
2 antibodies
NovoPro Bioscience Inc.
4 antibodies
Abnova Corporation
6 antibodies
Aviva Systems Biology
4 antibodies
OriGene
7 antibodies
ProSci
5 antibodies
HUABIO Research
1 antibody
Santa Cruz Biotechnology
1 antibody
LifeSpan BioSciences, Inc.
69 antibodies
Bioworld Technology, Inc
1 antibody
Affinity Biosciences
2 antibodies
Boster Biological Technology
3 antibodies
R&D Systems
1 antibody
Acris Antibodies GmbH
7 antibodies
St John's Laboratory
3 antibodies
Antibodies.com
1 antibody
MyBioSource
11 antibodies
United States Biological
51 antibodies
Creative Biolabs
9 antibodies
Leading Biology
5 antibodies
Atlas Antibodies
1 antibody
Abbexa
14 antibodies
Abiocode, Inc.
3 antibodies
Creative Diagnostics
6 antibodies
RabMAbs
2 antibodies
Cell Signaling Technology, Inc
1 antibody
Sigma-Aldrich
5 antibodies
RayBiotech, Inc.
1 antibody