Tissue expression
Cell line expression
Protein structure
EPHA2
EPH receptor A2ECK
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Mutations in this gene are the cause of certain genetically-related cataract disorders. [provided by RefSeq, May 2010]
Top validated antibodies |
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| Invitrogen Antibodies | 17 references | Polyclonal |
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| antibodies-online | 4 references | Monoclonal |
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| Novus Biologicals | 7 references | Polyclonal |
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| R&D Systems | 6 references | Polyclonal |
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| Boster Biological Technology | 1 references | Polyclonal |
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