Tissue expression
Cell line expression
Protein structure

OTX2

Orthodenticle homeobox 2
 
This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine. [provided by RefSeq, Jul 2012]
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526 antibodies from 38 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
Invitrogen Antibodies
29 antibodies
antibodies-online
148 antibodies
GeneTex
6 antibodies
OriGene
23 antibodies
Acris Antibodies GmbH
5 antibodies
R&D Systems
4 antibodies
Proteintech Group
1 antibody
Novus Biologicals
10 antibodies
Abnova Corporation
4 antibodies
Boster Biological Technology
3 antibodies
Biorbyt
92 antibodies
NovoPro Bioscience Inc.
4 antibodies
FineTest Biotech
2 antibodies
St John's Laboratory
5 antibodies
Cusabio Biotech Co., Ltd
6 antibodies
Abgent
8 antibodies
Affinity Biosciences
1 antibody
Atlas Antibodies
1 antibody
NSJ Bioreagents
6 antibodies
Aviva Systems Biology
3 antibodies
Arigo
2 antibodies
Bioworld Technology, Inc
1 antibody
Creative Biolabs
28 antibodies
Abbexa
11 antibodies
Creative Diagnostics
5 antibodies
MilliporeSigma / Merck KGaA
6 antibodies
ABEOMICS Inc.
2 antibodies
MyBioSource
8 antibodies
Leading Biology
8 antibodies
RabMAbs
4 antibodies
United States Biological
29 antibodies
Bioss
1 antibody
Cell Signaling Technology, Inc
1 antibody
Absolute Antibody
7 antibodies
EMD Millipore
1 antibody
ProSci
1 antibody
GenWay
1 antibody