TJP1

gene product
DKFZp686M05161, MGC133289, ZO-1
This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family of proteins, and acts as a tight junction adaptor protein that also regulates adherens junctions. Tight junctions regulate the movement of ions and macromolecules between endothelial and epithelial cells. The multidomain structure of this scaffold protein, including a postsynaptic density 95/disc-large/zona occludens (PDZ) domain, a Src homology (SH3) domain, a guanylate kinase (GuK) domain and unique (U) motifs all help to co-ordinate binding of transmembrane proteins, cytosolic proteins, and F-actin, which are required for tight junction function. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2017]
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Proteintech Group
3 antibodies
GeneTex
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Novus Biologicals
6 antibodies
Invitrogen Antibodies
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NovoPro Bioscience Inc.
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antibodies-online
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SICGEN
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OriGene
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LifeSpan BioSciences, Inc.
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Aviva Systems Biology
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NSJ Bioreagents
5 antibodies
Affinity Biosciences
2 antibodies
Rockland Immunochemicals, Inc.
2 antibodies
Boster Biological Technology
1 antibody
Biorbyt
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Cell Signaling Technology, Inc
3 antibodies
St John's Laboratory
5 antibodies
Arigo
4 antibodies
Abnova Corporation
6 antibodies
ProSci
2 antibodies
Signalway Antibody LLC
2 antibodies
Creative Diagnostics
6 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Antibodies.com
1 antibody
Bethyl Laboratories
1 antibody
HUABIO Research
1 antibody
Acris Antibodies GmbH
5 antibodies
Everest Biotech
1 antibody
Creative Biolabs
12 antibodies
Abgent
3 antibodies
MyBioSource
10 antibodies
United States Biological
26 antibodies
EMD Millipore
2 antibodies
Abbexa
5 antibodies
Abiocode, Inc.
1 antibody
RabMAbs
1 antibody
Sigma-Aldrich
3 antibodies