Tissue expression
Cell line expression
Protein structure
YWHAQ
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta14-3-3, HS1
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Proteintech Group | 15 references | Polyclonal |
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| Invitrogen Antibodies | Polyclonal |
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| LSBio | Polyclonal |
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| NovoPro Bioscience Inc. | Polyclonal |
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| OriGene | Monoclonal |
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