TERF2

This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic. [provided by RefSeq, Jul 2008]

Description

telomeric repeat binding factor 2

Protein family

Mapped to UniProt SWISS-PROT, Predicted intracellular proteins, Protein evidence (Ezkurdia et al 2014), Protein evidence (Kim et al 2014)

Chromosome

16:q22.1 (69355561 - 69408571)

Ensembl ID

ENSG00000132604  (ver. 84.38)

Orthologs

Mouse Terf2: ENSMUSG00000031921

UniProt

Q15554

neXtProt

NX_Q15554

Human splice variants
Mouse splice variants