PTEN

gene product
BZS, MHAM, MMAC1, PTEN1, TEP1
This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway. [provided by RefSeq, Jul 2008]
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1009 antibodies from 43 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
21 antibodies
GeneTex
26 antibodies
R&D Systems
11 antibodies
Enzo Life Sciences
1 antibody
Invitrogen Antibodies
14 antibodies
Cell Signaling Technology, Inc
14 antibodies
Abgent
25 antibodies
Bethyl Laboratories
4 antibodies
Biorbyt
114 antibodies
Acris Antibodies GmbH
34 antibodies
Abnova Corporation
31 antibodies
OriGene
47 antibodies
NSJ Bioreagents
18 antibodies
Signalway Antibody LLC
4 antibodies
NovoPro Bioscience Inc.
19 antibodies
Affinity Biosciences
7 antibodies
Boster Biological Technology
6 antibodies
LifeSpan BioSciences, Inc.
3 antibodies
Bioworld Technology, Inc
8 antibodies
Proteintech Group
2 antibodies
St John's Laboratory
23 antibodies
ProSci
5 antibodies
Antibodies.com
1 antibody
Abbkine Scientific Co.Ltd.
12 antibodies
RabMAbs
15 antibodies
Abbiotec
3 antibodies
SignalChem
2 antibodies
antibodies-online
11 antibodies
EMD Millipore
8 antibodies
Creative Diagnostics
14 antibodies
Creative Biolabs
8 antibodies
Arigo
1 antibody
BioLegend
1 antibody
Rockland Immunochemicals, Inc.
1 antibody
United States Biological
470 antibodies