Tissue expression
Cell line expression
Protein structure
RELA
RELA proto-oncogene, NF-kB subunitNFKB3, p65
NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Top validated antibodies |
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Proteintech Group | ![]() |
1293 references | Polyclonal |
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Invitrogen Antibodies | ![]() |
15 references | Polyclonal |
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GeneTex | ![]() |
28 references | Polyclonal |
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Novus Biologicals | ![]() |
27 references | Polyclonal |
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Boster Biological Technology | ![]() |
98 references | Polyclonal |
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