DNMT3B

gene product
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined. [provided by RefSeq, May 2011]
More gene data

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI
517 antibodies from 41 providers.

Antibody properties

General

Applications

or Cancel
Antibody
GeneTex
8 antibodies
antibodies-online
183 antibodies
Novus Biologicals
6 antibodies
Cell Signaling Technology, Inc
6 antibodies
Invitrogen Antibodies
11 antibodies
OriGene
11 antibodies
Abgent
5 antibodies
Enzo Life Sciences
1 antibody
Abnova Corporation
10 antibodies
Biorbyt
33 antibodies
Acris Antibodies GmbH
7 antibodies
Aviva Systems Biology
3 antibodies
LifeSpan BioSciences, Inc.
82 antibodies
Affinity Biosciences
3 antibodies
HUABIO Research
2 antibodies
Atlas Antibodies
1 antibody
Proteintech Group
1 antibody
R&D Systems
1 antibody
Bioworld Technology, Inc
2 antibodies
St John's Laboratory
4 antibodies
Boster Biological Technology
2 antibodies
Arigo
1 antibody
NSJ Bioreagents
1 antibody
ProSci
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Rockland Immunochemicals, Inc.
1 antibody
Creative Biolabs
17 antibodies
Creative Diagnostics
4 antibodies
Active Motif
2 antibodies
Abbexa
15 antibodies
ABEOMICS Inc.
2 antibodies
United States Biological
53 antibodies
RabMAbs
2 antibodies
BioLegend
1 antibody
RayBiotech, Inc.
1 antibody
Miltenyi Biotec
5 antibodies
MyBioSource
4 antibodies
Sigma-Aldrich
2 antibodies
Abbiotec
1 antibody
EMD Millipore
1 antibody