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Protein structure
CTSD
Cathepsin DCLN10, CPSD
This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. [provided by RefSeq, Nov 2015]
Top validated antibodies |
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| Novus Biologicals |  NBP1-04278 |
4 references | Monoclonal |
WB
EL
ICC
IHC
FC
IEM
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| Proteintech Group | 21327-1-AP |
105 references | Polyclonal |
WB
EL
ICC
IHC
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| GeneTex | GTX62063 |
5 references | Monoclonal |
WB
ICC
IP
IHC
FC
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| R&D Systems | AF1029 |
11 references | Polyclonal |
WB
ICC
IP
IHC
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| Abnova Corporation | H00001509-M01 |
1 references | Monoclonal |
WB
EL
IP
IHC
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