S100B

gene product
S100beta
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes. [provided by RefSeq, Jul 2008]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI
1703 antibodies from 41 providers.

Antibody properties

General

Applications

or Cancel
Antibody
Atlas Antibodies
2 antibodies
Invitrogen Antibodies
20 antibodies
Novus Biologicals
253 antibodies
Proteintech Group
2 antibodies
GeneTex
16 antibodies
NSJ Bioreagents
15 antibodies
antibodies-online
742 antibodies
Biorbyt
65 antibodies
R&D Systems
2 antibodies
OriGene
43 antibodies
NovoPro Bioscience Inc.
6 antibodies
Boster Biological Technology
4 antibodies
Abnova Corporation
22 antibodies
Abgent
6 antibodies
LifeSpan BioSciences, Inc.
215 antibodies
Acris Antibodies GmbH
16 antibodies
Affinity Biosciences
1 antibody
ProSci
4 antibodies
Bioworld Technology, Inc
1 antibody
St John's Laboratory
5 antibodies
Sigma-Aldrich
3 antibodies
Abbexa
4 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Antibodies.com
1 antibody
Aviva Systems Biology
7 antibodies
Arigo
3 antibodies
RabMAbs
2 antibodies
Creative Biolabs
51 antibodies
MyBioSource
24 antibodies
BioLegend
3 antibodies
GenWay
13 antibodies
Creative Diagnostics
5 antibodies
United States Biological
105 antibodies
Spring Bioscience
4 antibodies
Abbiotec
3 antibodies
RayBiotech, Inc.
9 antibodies
Leading Biology
4 antibodies
EMD Millipore
2 antibodies
Cell Signaling Technology, Inc
1 antibody
BioLegend (formerly Covance Antibody Products)
2 antibodies